Christian Raisson and Philippe de Chanville registered the company on 26 July 2012 as Colibri SAS, with €150,000 in capital. The site went live in June 2013 as MonEchelle.fr, a DIY shop whose name meant "my ladder".
Business angels added €300,000 in 2013, and about €2 million followed in 2014. In September 2015 the company was renamed ManoMano, a name that worked in French, Spanish and Italian. Spain and Italy opened that year, the UK in 2016 and Germany in November 2016.
Larger rounds followed: €13 million in 2016, €60 million from General Atlantic in 2017 and €125 million with Temasek in 2020. In 2020 the company reached €1.2 billion in business volume. A $355 million round in July 2021 valued it at about $2.6 billion.
In October 2023 ManoMano announced a restructuring plan that included 230 job cuts. In April 2026 Raisson stepped back after serving as CEO, and Loic Derrien took over as chief executive.