Aengus Tran was born in Ho Chi Minh City and moved to Sydney at 14. His father was a teacher in Vietnam who owned one of the country's first computers. His brother Dimitry, who arrived in Sydney at 22, studied accounting and paid for Aengus's medical degree at UNSW.
As a student Aengus built an AI tool to help choose which IVF embryos to implant. The work showed the brothers that AI could spread scarce clinical expertise. They founded Harrison.ai in Sydney in 2018, with Aengus as CEO.
In 2021 the company formed annalise.ai with I-MED Radiology. It later formed franklin.ai with Sonic Healthcare for pathology. In November 2021 it raised a A$129 million Series B, with Horizons Ventures.
In February 2025 Harrison.ai raised a Series C of A$179 million, co-led by Aware Super, ECP and Horizons Ventures, with the National Reconstruction Fund Corporation. By 2025 it held 12 FDA clearances and clearance in 40 countries, with products in more than 1,000 facilities.